On September 11, 2018, Bloomberg Environment Insights published a three-part article series, written by Bergeson & Campbell, P.C. (B&C®), on the impact of the new Toxic Substances Control Act (TSCA) Section 5 and its implementation. Despite the U.S. Environmental Protection Agency’s (EPA) overall timely and balanced efforts in the implementation of TSCA, EPA’s approach to TSCA Section 5 implementation has proved itself less successful. With emphasis on how EPA’s approach to Section 5 has impeded the commercialization of sustainable chemical technologies, this three-part series delves into the various challenges presented by TSCA on the biobased and biotechnology markets. The obstacles discussed in the articles, ironically, often extend the market presence of less sustainable chemicals rather than allowing for the expansion of more sustainable technologies. The three articles can be accessed here: Part 1, Part 2, and Part 3.