On March 29, 2018, the U.S. Environmental Protection Agency (EPA) announced in a Federal Register notice it is seeking public comment on the use of isobutanol in gasoline. EPA specifically seeks comment on issues to consider regarding an application submitted by Butamax Advanced Biofuels, LLC (Butamax), a manufacturer of isobutanol, pursuant to the regulations titled “Registration of Fuels and Fuel Additives” for the registration of isobutanol as a gasoline additive at up to 16 volume percent, and any supplemental actions EPA should consider under the Clean Air Act (CAA). EPA states that Butamax’s information would likely satisfy the applicable registration requirements, and, due to the likelihood of this registration, there is potential for the widespread introduction of isobutanol into commerce. Further information on biobutanol, the common name for isobutanol made from renewable sources, is available in the Federal Register notice. Comments are due by April 30, 2018.