On March 22, 2018, the U.S. Department of Energy’s (DOE) National Renewable Energy Laboratory (NREL) announced that by studying and comparing the cellulose-degrading enzymes of two fungi, NREL researchers have pinpointed regions on these enzymes that can be targeted via genetic engineering to help break down cellulose faster. The article published in Nature Communications, “Engineering enhanced cellobiohydrolase activity,” describes NREL’s long-running study of the fungal cellobiohydrolases (CBH) -- enzymes that use hydrolysis as their main chemistry to degrade cellulose -- Trichoderma reesei (TrCel7A) and Penicillium funiculosum (PfCel7A). The announcement states that in both nature and industrial processes, enzymes from this family are among the most significant enzymes for breaking down cellulose; a “projected 2,000-ton-per-day cellulosic ethanol plant could potentially use up to 5,000 tons of enzyme per year, and half of that enzyme cocktail could be from this enzyme family.”
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Researchers at the DOE National Renewable Energy Laboratory (NREL) are seeking responses to a survey on biorefinery operations. Yimin Zhang, an environmental engineer at NREL, and Marshall Goldberg, a subcontractor for NREL, developed the brief survey to improve the NREL’s understanding of the next generation biofuel industry and its contribution to the local, state, and national economy. Industry stakeholders in the planning, construction, or operation stage of a biorefinery are asked to complete the survey by March 8, 2018. The aggregate data will be used to report the survey results. Individual responses will not be published.
On November 29, 2017, the U.S. Department of Energy (DOE) announced that a collaboration between the National Renewable Energy Laboratory (NREL) and Oak Ridge National Laboratory (ORNL) resulted in the successful modification of a microorganism to produce a versatile fermentation intermediate that can be upgraded into valuable biobased fuels and chemicals. NREL’s cellulosic ethanol fermentation organism (Zymomonas mobilis), is capable of exclusively producing 2,3-butanediol (2,3-BDO), which can be catalytically upgraded to a variety of hydrocarbon fuel precursors and valuable chemical co-products. Techno-economic modeling was performed to study the potential of producing hydrocarbon fuel precursors and co-products in a cost effective manner. The first breakthrough occurred with genetic modifications to eliminate the ethanol pathways to ensure that sugar metabolism pathways also produced 2,3-BDO. ORNL continues to explore modifications to its catalytic upgrading system to achieve further process simplifications and cost savings. On September 26, 2017, the U.S. Department of Energy (DOE) announced the selection of an additional project for the Bioenergy Technologies Office’s (BETO) Advanced Algal Systems Program funding opportunity announcement (FOA). DOE is awarding up to $3.5 million to the National Renewable Energy Laboratory (NREL) to more than double the productivity of biofuel precursors from algae. Researchers aim to improve productivity by increasing algal cultivation productivity, optimizing biomass composition, and extracting and separating different types of algal lipids to reduce the cost for lipid upgrading to renewable diesel. The project team includes researchers from NREL, as well as Colorado State University, Colorado School of Mines, Arizona State University, Sandia National Laboratories, POS Bio-Sciences, Sapphire Energy, and Utah State University. |
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